ACP Journal Club. Adding Na/K citrate to standard hydration reduced CIN in patients having coronary angiography.
نویسنده
چکیده
Commentary Definitive evidence of how best to prevent CIN is lacking despite numerous studies. Markota and colleagues found that 5 g of oral Na/K citrate given 1 hour before coronary angiography and then 4 hours later resulted in a 17% absolute risk reduction in CIN at 48 hours after catheterization. Post hoc analysis showed a 93% relative risk reduction (RRR) in CIN in patients with urinary pH > 6 at angiography compared with those with pH < 6.
منابع مشابه
Prevention of contrast-induced nephropathy with Na/K citrate.
AIMS Contrast-induced nephropathy (CIN) is a frequent complication of many radiological procedures involving the application of contrast media. It represents a significant health problem that causes the increase in mortality, morbidity, and medical costs. For the prevention of CIN, a number of methods have been proposed to be effective. Among them, alkalinization of urine takes an important pla...
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Coronary angiography can be a high-risk condition for the incidence of contrast-induced nephropathy (CIN) in elderly patients. Reduced glutathione, under a variety of mechanisms, may prevent CIN in this procedure. We prospectively examined whether hydration with reduced glutathione is superior to hydration alone for prevention of CIN in an elderly Han Chinese population. A total of 505 patients...
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Background and purpose: N-Acetylcysteine (NAC) has been found to reduce the risk of Contrast Induced Nephropathy (CIN) in chronic renal insufficiency after CT imaging with contrast enhancement. The purpose of the current study was to evaluate the efficacy of NAC, for the prevention of CIN in normal renal functioning patients undergoing coronary angiography. Materials and Methods: We prospe...
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A Randomized Double Blind Placebo Controlled Trial Examining the Effects of Pentoxifylline on Contrast Induced Nephropathy Reduction after Percutaneous Coronary Intervention in High Risk Candidates
Contrast-induced nephropathy (CIN) (known as contrast-induced acute kidney injury) occurs as a result of acute worsening of renal function following a procedure with administration of iodine contrasts agent and remains a substantial concern in clinical practices. The purpose of this study is to investigate the preventive effect of Pentoxifylline supplementation on reduction of CIN occurrence af...
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ورودعنوان ژورنال:
- Annals of internal medicine
دوره 158 12 شماره
صفحات -
تاریخ انتشار 2013